Table 4.

Associations Between Life’s Simple 7 Components and CMR Imaging Indices

Ideal Cardiovascular HealthLV Mass Index, g/m2.7*LV Concentric Remodeling Index, g/mL*Peak Global Strain (%)Aortic PWV, m/s*
LS MeanP ValueLS meanP ValueLS MeanP ValueLS MeanP Value
Nonsmoking28.950.010.98<0.0001−16.110.00025.200.0001
Smoking30.321.07−15.316.09
Ideal BMI26.65<0.00010.97<0.0001−16.12<0.00015.900.01
Nonideal BMI32.931.09−15.295.36
Ideal nutrition29.650.980.980.34−15.890.664.610.02
Nonideal nutrition29.601.07−15.536.87
Ideal physical activity29.610.941.030.95−15.780.375.710.33
Nonideal physical activity29.641.03−15.645.54
Ideal BP28.38<0.00010.98<0.0001−15.800.285.510.17
Nonideal BP30.921.07−15.625.75
Ideal fasting plasma glucose28.860.0021.010.15−15.950.015.700.51
Nonideal fasting plasma glucose30.411.04−15.475.56
Ideal total cholesterol29.970.061.020.35−15.720.905.620.94
Nonideal total cholesterol29.291.03−15.705.63
  • Linear models were constructed for each imaging parameter (dependent variable) as a function of age, sex, and each Simple 7 component to obtain least squares means. All Simple 7 components were included simultaneously in the same model. P values of <0.007 were considered significant using Bonferroni correction. BMI indicates body mass index; BP, blood pressure; CMR, cardiac magnetic resonance; LS, least squares; LV, left ventricle; and PWV, pulse wave velocity.

  • * Least squares means of log-transformed variables (LV mass index, LV concentric remodeling index, and aortic PWV) were exponentiated.